Steffen Backert’s Fighting Campylobacter Infections 431 Volume pdf free download with direct link.This modified volume detects Campylobacter species, some of the major food-borne pathogens. Above all, contaminated poultry meat can cause human gastritis in both developed and developing countries. Relevant partnerships show how these infections can increase the risk of common stroke diseases such as Gillian-Berry syndrome, Miller-Fisher syndrome, and Chinese stroke syndrome. Because of their influence on the nervous system, circulatory system and various organs, Campylobacter infections represent a serious health concern.
Campylobacter can be effectively counteracted by addressing hygiene conditions in both food production and human lifestyles. Accordingly, the authors presented a health approach, which provides readers with practical guidance on the basic biology of Campelobacter, as well as aspects ranging from food production to clinical treatment of infections.
Fighting Campylobacter Infections PDF Free Medical Book related to Microbiology and Immunology (CTMI)
|Book Name||Fighting Campylobacter Infections|
|Author of Book||Steffen Backert|
Steffen Backert is Professor of Microbiology in the Department of Biology, Friedrich Alexander University, Erlangen-Nuremberg, Germany. His group has been working in the field of microbial pathogenesis for nearly 25 years, investigating molecular signaling pathways during the interaction of host pathogens in internal infections such as Campylobacter gigioni and Helicobacter pylori. His research interest focuses on the identification and characterization of new bacterial virulence factors (secret or injection), which may represent potential novel targets of treatment. He has authored more than 220 peer-reviewed publications and edited eight scientific books. He is an associate editor of various top research journals and has a strong and consistent record of receiving competitive research funding. Professor Beckert has invented five patents.
Topics of this Edition:
Human Campylobacteriosis—A Serious Infectious Threat in a One Health Perspective ……………………………. 1
The Data Behind Risk Analysis of Campylobacter Jejuni and Campylobacter Coli Infections ……………………….. 25
Population Biology and Comparative Genomics of Campylobacter Species ……………………………… 59
Management Strategies for Prevention of Campylobacter Infections Through the Poultry Food Chain: A European Perspective ………. 79
Emission Sources of Campylobacter from Agricultural Farms, Impact on Environmental Contamination and Intervention Strategies …….. 103
Phage Biocontrol of Campylobacter: A One Health Approach ……. 127
Campylobacter Virulence Factors and Molecular Host–Pathogen Interactions …. 169
Diarrheal Mechanisms and the Role of Intestinal Barrier Dysfunction in Campylobacter Infections .203
Murine Models for the Investigation of Colonization Resistance
and Innate Immune Responses in Campylobacter Jejuni Infections …. 233
Natural Competence and Horizontal Gene Transfer
in Campylobacter …………………………………… 265
Molecular Mechanisms of Campylobacter Biofilm Formation
and Quorum Sensing ………………………………… 293
This index belogs to Fighting Campylobacter Infections PDF Free download
Food-borne microbial infections of the human gastrointestinal tract and resulting diseases are associated with very high degrees of morbidity and mortality in the world’s population. According to the World Health Organization (WHO 2020), unsafe food products cause 600 million cases of food-borne diseases and 420,000 deaths annually, especially in children and elderly people. The WHO calculated that about 33 million years of healthy lives are lost through eating unsafe food worldwide every year, and this number is likely an underestimation (WHO 2020). Over the past two decades, Campylobacter jejuni has been recognized as the leading source of bacterial gastroenteritis around the globe (Wassenaar and Blaser 1999; Young et al. 2007; Altekruse 2008; Dasti et al. 2010; Burnham and Hendrixson 2018). Gut disease outcomes vary from mild, non-inflammatory, self-limiting diarrhea to severe, inflammatory, bloody diarrhea associated with severe abdominal pain, which can last for a few weeks. However, C. jejuni-infection is also associated with more severe neurological sequelae in some patients, such as the Guillain-Barré syndrome (GBS) and the Miller Fisher syndrome (MFS) (Talukder et al. 2011; Wakerley et al. 2014). Statistical evaluations indicate that Campylobacter infections are responsible for considerable costs of medication and health service. In the USA alone, it was estimated that Campylobacter illnesses in humans cost a burden of up to $6.2 billion annually (Forsythe 2000). In fact, in numerous studies from the USA and other developed nations, Campylobacter was reported to cause diarrheal disease 2–7 times more frequently than pathogenic Salmonella,Escherichia or Shigella species.
Fig. 1 Annual incidences of infections with intestinal bacterial pathogens in Germany. These
data are derived from the yearly German Disease Statistics Reports for 2006 and 2019 as published
by the Robert Koch Institute (RKI), Berlin (Germany). While the reported number of salmonellosis
cases has slightly fallen from 19,531 to 13,281, those of campylobacteriosis rose from 22,390 to
55,959 in the shown years.
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