Now in its fourth edition, Laboratory Design Guidelines enable readers to design labs that enable scientific research in a safe and healthy environment. Guidelines for Laboratory Design 4th Edition PDF brings together all the professionals who are critical to a successful lab design, discussing the role of architects, engineers, health and safety professionals, and laboratory researchers. It provides the design team with the information they need to ask the right questions and then determine the best design while adhering to existing regulations and best practices.
Guidelines for Laboratory Design: Health, Safety, and Environmental Considerations, 4th Edition is available free to download on this page.
Table of Contents
Key Features
Laboratory Design Guidelines provide brief, straightforward information in an easy-to-use, safe, and effective format. Divided into five sections, the book lists the most important and completed conclusions:
- Section IA, Principles of Functional Development, describes specific instructions that apply to most laboratories and standards.
IB, Common Elements of Innovation, provides design solutions for the design and modernization of existing test sites - Part II, Development Guides for Multidimensional Equipment, describes special instructions, best practices, and instructions for 19 types of experiments, including three new chapters that include Nanotechnology, Engineering, and the Autopsy Lab.
- Part III, Service Lab, includes design issues for laboratories, support stores, hazardous waste sites, and clinics.
- Part IV, HVAC Systems, describes how to heat, cool and ventilate a test room with energy-efficient pressure.
- Part V, Management procedures, test procedures, final inspection and safety.
At the end of the book, there are usually five more pages with the necessary information and reference material.
Overview:
| Book Name | Guidelines for Laboratory Design |
| Author | Louis J. DiBerardinis, Janet S. Baum, Melvin W. First, Gari T. Gatwood, Anand K. Se |
| Edition | 4th |
| Language | English |
| Format | |
| Category | Laboratory Books |
Topics of this Edition:
PREFACE xvii
ACKNOWLEDGMENTS xix
ABOUT THE AUTHORS xxi
ABBREVIATIONS xxiii
UNITS xxv
ORGANIZATIONS REFERENCED xxvii
INTRODUCTION xxix
How to Use This Book, xxx
Book Organization, xxxi
Computational Fluid Dynamics, xxxiii
PART IA COMMON ELEMENTS OF LABORATORY DESIGN 1
1 Building Considerations 3
1.1 Guiding Concepts, 3
1.2 Building Layout, 3
1.3 Guiding Principles for Building Heating, Ventilating, and Air-Conditioning Systems, 44
1.4 Guiding Concepts for Laboratory Building Loss Prevention, Industrial Hygiene, and Personal Safety, 51
1.5 Miscellaneous Services, 56
2 Laboratory Considerations 65
PART IB COMMON ELEMENTS OF RENOVATIONS 109
3 Renovations: Building Considerations 123
3.1 Guiding Concepts, 123
3.2 Building Layout, 125
3.3 Heating, Ventilating, and Air-Conditioning Systems, 129
3.4 Loss Prevention, Industrial Hygiene, and Personal Safety, 133
3.5 Miscellaneous Services, 134
4 Renovations: Laboratory Considerations 136
4.1 Guiding Concepts, 136
4.2 Laboratory Layout, 137
4.3 Heating, Ventilating, and Air-Conditioning Systems, 138
4.4 Loss Prevention, Industrial Hygiene, and Personal Safety, 138
PART II DESIGN GUIDELINES FOR A NUMBER OF COMMONLY USED LABORATORIES 141
5 General or Analytical Chemistry Laboratory 143
5.1 Description, 143
5.2 Laboratory Layout, 144
5.3 Heating, Ventilating, and Air-Conditioning, 146
5.4 Loss Prevention, Industrial Hygiene, and Personal Safety, 149
5.5 Special Requirements, 149
6 High-Toxicity Laboratory 150
6.1 Description, 150
6.2 Laboratory Layout, 151
6.3 Heating, Ventilating, and Air-Conditioning, 153
6.4 Loss Prevention, Industrial Hygiene, and Personal Safety, 154
6.5 Special Requirements, 155
7 Nanotechnology Laboratories 156
7.1 Description, 156
7.2 Laboratory Layout, 156
7.3 Heating, Ventilating, and Air-Conditioning, 157
7.4 Loss Prevention, Industrial Hygiene, and Personal Safety, 158
8 Engineering Laboratories 160
8.1 Description, 160
8.2 Engineering Disciplines and Some of Their Most Common Laboratory Types, 160
8.3 Wind Tunnel Laboratory, 161
8.4 Jet and Rocket Propulsion Laboratory, 162
8.5 Hydraulics Laboratory, 164
8.6 Material Analysis and Testing Laboratory, 165
8.7 Electrical Circuits, Motors, and Generators Laboratory, 165
8.8 Foundry Laboratory, 167
8.9 Internal Combustion and Gas Turbine Engine Laboratory, 169
9 Pilot Plant: Chemical, Engineering, and Biological 173
9.1 Description, 173
9.2 Pilot Plant Layout, 174
9.3 Heating, Ventilating, and Air-Conditioning, 174
9.4 Loss Prevention, Industrial Hygiene, and Personal Safety, 175
9.5 Special Requirements, 175
10 Physics Laboratory 177
10.1 Description, 177
10.2 Laboratory Layout, 178
10.3 Heating, Ventilating, and Air-Conditioning, 179
10.4 Loss Prevention, Industrial Hygiene, and Personal Safety, 179
10.5 Special Requirements, 181
11 Controlled Environment Room: Hot or Cold 182
11.1 Description, 182
11.2 Laboratory Layout, 183
11.3 Heating, Ventilating, and Air-Conditioning, 183
11.4 Loss Prevention, 185
11.5 Special Requirements, 185
12 High-Pressure Laboratory 187
12.1 Description, 187
12.2 Laboratory Layout, 188
12.3 Heating, Ventilating, and Air-Conditioning, 188
12.4 Loss Prevention, Industrial Hygiene, and Personal Safety, 189
12.5 Special Requirements, 189
13 Radiation Laboratory 190
13.1 Description, 190
13.2 Laboratory Layout, 191
13.3 Heating, Ventilating, and Air-Conditioning, 194
13.4 Loss Prevention, Industrial Hygiene, and Personal Safety, 195
13.5 Special Considerations, 195
14 Biosafety Laboratory 196
14.1 Description, 196
14.2 Laboratory Layout, 202
14.3 Heating, Ventilating, and Air-Conditioning, 212
14.4 Loss Prevention, Industrial Hygiene, and Personal Safety, 213
14.5 Special Requirements, 213
15 Clinical Laboratories 216
15.1 Description, 216
15.2 Laboratory Layout, 218
15.3 Heating, Ventilating, and Air-Conditioning, 222
15.4 Loss Prevention, Industrial Hygiene, and Personal Safety, 223
16 Teaching Laboratory 227
16.1 Description, 227
16.2 Laboratory Layout, 228
16.3 Heating, Ventilating, and Air-Conditioning, 234
16.4 Loss Prevention, Industrial Hygiene, and Personal Safety, 235
17 Gross Anatomy Laboratory 238
17.1 Description, 238
17.2 Laboratory Layout, 239
17.3 Heating, Ventilating, and Air-Conditioning, 243
17.4 Loss Prevention, Industrial Hygiene, and Personal Safety, 244
17.5 Security, 245
18 Pathology Laboratory 246
18.1 Description, 246
18.2 Laboratory Layout, 249
18.3 Heating, Ventilating, and Air-Conditioning, 251
18.4 Loss Prevention, Industrial Hygiene, and Personal Safety, 251
18.5 Special Requirements, 252
19 Autopsy Laboratory 253
19.1 Description, 253
19.2 Laboratory Layout, 255
19.3 Heating, Ventilating, and Air-Conditioning, 260
19.4 Loss Prevention, Industrial Hygiene, and Personal Safety, 261
20 Morgue Facility 262
20.1 Description, 262
20.2 Laboratory Layout, 265
20.3 Heating, Ventilating, and Air-Conditioning, 269
20.4 Loss Prevention, Industrial Hygiene, and Personal Safety, 269
21 Open or Team Research Laboratory 271
21.1 Description, 271
21.2 Laboratory Layout, 272
21.3 Heating, Ventilating, and Air-Conditioning, 275
21.4 Loss Prevention, Industrial Hygiene, and Personal Safety, 275
21.5 Special Considerations, 276
22 Animal Research Laboratory 277
22.1 Description, 277
22.2 Laboratory Layout, 279
22.3 Heating, Ventilating, and Air-Conditioning, 292
22.4 Loss Prevention, Industrial Hygiene, and Personal Safety, 296
22.5 Special Requirements, 297
23 Microelectronics and Cleanroom Laboratories 299
23.1 Description, 299
23.2 Laboratory Layout, 303
23.3 Heating, Ventilating, and Air Conditioning, 307
23.4 Loss Prevention, Industrial Hygiene, and Personnel Safety, 310
23.5 Special Requirements, 312
23.6 Renovations, 314
24 Printmaking Studio 315
24.1 Description, 315
24.2 Print Studio Layout, 317
24.3 Heating, Ventilating, and Air-Conditioning, 318
24.4 Loss Prevention, Industrial Hygiene, and Personal Safety, 321
PART III LABORATORY SUPPORT SERVICES 325
25 Imaging and Photographic Facilities 327
25.1 Introduction, 327
25.2 Photographic And Imaging Facility Layouts, 331
25.3 Heating, Ventilating, and Air-Conditioning, 334
25.4 Loss Prevention, Industrial Hygiene, and Personal Safety, 336
25.5 Special Requirements, 337
26 Support Shops 339
26.1 Description, 339
26.2 Layout, 340
26.3 Heating, Ventilating, and Air-Conditioning, 344
26.4 Loss Prevention, Industrial Hygiene, and Personal Safety, 346
26.5 Special Requirements, 346
27 Hazardous Chemical, Radioactive, and Biological Waste-Handling Rooms 348
27.1 Guiding Concepts, 348
27.2 Layout, 351
27.3 Heating, Ventilating, and Air-Conditioning, 356
27.4 Loss Prevention, Industrial Hygiene, and Personal Safety, 358
27.5 Special Requirements, 358
28 Laboratory Storerooms 360
28.1 Description, 360
28.2 Layout, 363
28.3 Heating, Ventilating, and Air-Conditioning, 366
28.4 Loss Prevention, Industrial Hygiene, and Personal Safety, 367
28.5 Special Requirements, 368
PART IV HVAC SYSTEMS 369
29 HVAC Systems 371
29.1 Description, 371
29.2 Air-Conditioning Systems, 371
29.3 HVAC System Design and Description, 376
29.4 System Descriptions and Strategies, 377
29.5 Humidification and Dehumidification, 386
29.6 Space Pressure Control, 389
29.7 Automatic Control System, 391
30 Fans 392
30.1 Fan Terminology, 392
30.2 Exhaust Fan Specifications, 393
30.3 Atmospheric Dispersion, 394
30.4 Fan Laws, 394
30.5 Fan Selection, 395
30.6 Fan Performance, 396
31 Air Cleaning 397
31.1 Introduction, 397
31.2 Air-Cleaning Equipment for Laboratories, 398
32 Laboratory Hoods and Other Exhaust Air Contaminant-Capture Facilities and Equipment 404
32.1 Introduction, 404
32.2 Conventional Bypass Chemical Fume Hoods, 405
32.3 Auxiliary Air Chemical Fume Hoods, 409
32.4 Perchloric Acid Fume Hoods, 411
32.5 Hoods for Work With Radioactive Materials, 411
32.6 Variable Air-Volume Hoods, 411
32.7 High-Performance Hoods, 412
32.8 Gloveboxes, 412
32.9 Biological Safety Cabinets, 413
32.10 Capture (Exterior) Hoods, 416
32.11 Ductless Hoods, 416
32.12 Performance Tests, 420
33 Exhaust Air Ducts and Accessories 422
33.1 Introduction, 422
33.2 Exhust Duct Considerations, 423
33.3 Exhust System Classification, 424
33.4 Duct Accessories, 424
34 Variable-Air-Volume Systems 426
34.1 Introduction, 426
34.2 VAV Hoods, 427
34.3 Good Design Practices for Vav Systems, 428
34.4 Variable-Volume Exhaust System Operational Concept, 428
34.5 VAV System Controls and Components, 429
34.6 VAV System Fan Controls and Components, 431
34.7 VAV System Duct Configurations, 434
35 Energy Conservation 436
35.1 Introduction, 436
35.2 Recent Trends, 437
35.3 Exhaust Ventilation for Contamination Control, 440
35.4 Lighting, 448
35.5 Thermal Insulation, 448
35.6 Humidity Control, 448
35.7 Evaporative Cooling, 449
35.8 Water Conservation, 449
35.9 Efficient Operating Strategies, 449
PART V ADMINISTRATIVE PROCEDURES 451
36 Project Execution and Bidding Procedures 453
36.1 Guiding Concepts, 453
36.2 Implementation, 454
36.3 Bid Form, 456
36.4 Contract, 457
36.5 Change Orders, 457
36.6 Construction Inspections, 458
36.7 Punch List, 458
36.8 Additional Testing and Acceptance, 458
36.9 Beneficial Occupancy, 459
36.10 Final Acceptance and Commissioning, 459
37 Commissioning and Final Acceptance Criteria 460
37.1 Guiding Concepts, 460
37.2 Design, Construction, and Preoccupancy Checklists, 460
37.3 Heating, Ventilating, and Air-Conditioning, 462
37.4 Loss Prevention, Industrial Hygiene, and Personal Safety, 466
37.5 Project Commissioning, 467
38 Sustainable Laboratory Design 471
38.1 Introduction, 471
38.2 Laboratory Construction Materials, 472
38.3 Heating, Ventilating, and Air-Conditioning, 474
38.4 Loss Prevention, Industrial Hygiene, and Personal Safety, 477
38.5 Miscellaneous Services, 477
38.6 Lighting, 478
38.7 Submetering, 479
38.8 Additional Background Material, 479
PART VI APPENDIXES 481
Appendix A Emergency Showers 483
Appendix B Emergency Eyewash Units 485
Appendix C Signs 486
Appendix D Stack Design 489
Appendix E Matrix of Building Consideration for Specific
Laboratory Types 495
REFERENCES 500
INDEX 509
Introduction:
Today, the laboratory is an incubator for the discoveries of tomorrow. The nature of laboratory work requires the use of potentially hazardous materials, complex equipment that must be combined with internal procedures and technical procedures. Therefore, it is important that the laboratory establishes safety and health first. The design, construction and operation of labs and labs alone can be cumbersome and difficult, requiring a balance of size, cost, and variability when utilizing work capacity.
Safe and efficient As new technologies emerge and new discoveries are made, laboratories must evolve to stay ahead of research. An important part of this change is the implementation of risk assessments that address a wide range of laboratory conditions. Risk assessments should be conducted to determine the risk and the construction or safety procedures that should be used to ensure the safety of workers and the environment. Risk assessment is a specialized and redefining process that addresses the appropriate objectives for agent risk and laboratory work. The results of the risk assessment should be documented and kept on file at the facility on a permanent basis.
The problems identified in the risk assessment should be addressed in the corrective action plan which should be used to follow the corrective action. Regular risk assessments should be carried out until remedied.
Commissioning is a great process for validating and documenting that a facility and its structures are planned, designed, installed, tested, and able to being operated and maintained to carry out in conformity with the layout rationale. Commissioning starts with the making plans segment of a given venture and proceeds thru layout, construction, start-up, training, acceptance, and early occupancy. The commissioning manner is designed to make certain compliance with the layout rationale of the facility.
Commissioning partly makes a specialty of how the engineering controls observe the general constructing operations. There are several different tactics that can be taken into consideration as a part of the layout and persevering with the operation of a secure laboratory. These consist of improvement of widespread working procedures, verification of character and included structures, certification of specialized laboratories, and compliance to country-wide and global requirements or relevant neighborhood policies.
This -e-book gives a clean to apply roadmap for proprietors and architects to fulfill the numerous demanding situations inherent in laboratories from the most effective to the maximum complex. It brings collectively the various specialists who’re vital to a successful layout: architects, engineers, fitness and protection specialists, and give up users. It gives the layout group vital data for them to invite the best questions and decide what’s the pleasant layout for the unique forms of laboratories desired, at the same time as guiding them withinside the compliance with the applicable policies and contemporary pleasant practices.
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