Guidelines for Laboratory Design

Guidelines for Laboratory Design 4th Edition PDF Free google drive

Now in its fourth edition, Laboratory Design Guidelines enable readers to design labs that enable scientific research in a safe and healthy environment. Guidelines for Laboratory Design 4th Edition PDF brings together all the professionals who are critical to a successful lab design, discussing the role of architects, engineers, health and safety professionals, and laboratory researchers. It provides the design team with the information they need to ask the right questions and then determine the best design while adhering to existing regulations and best practices.

Guidelines for Laboratory Design: Health, Safety, and Environmental Considerations, 4th Edition is available free to download on this page.

Key Features

Laboratory Design Guidelines provide brief, straightforward information in an easy-to-use, safe, and effective format. Divided into five sections, the book lists the most important and completed conclusions:

  • Section IA, Principles of Functional Development, describes specific instructions that apply to most laboratories and standards.
    IB, Common Elements of Innovation, provides design solutions for the design and modernization of existing test sites
  • Part II, Development Guides for Multidimensional Equipment, describes special instructions, best practices, and instructions for 19 types of experiments, including three new chapters that include Nanotechnology, Engineering, and the Autopsy Lab. 
  • Part III, Service Lab, includes design issues for laboratories, support stores, hazardous waste sites, and clinics.
  • Part IV, HVAC Systems, describes how to heat, cool and ventilate a test room with energy-efficient pressure.
  • Part V, Management procedures, test procedures, final inspection and safety.
    At the end of the book, there are usually five more pages with the necessary information and reference material.

Overview:

Book Name Guidelines for Laboratory Design
Author  Louis J. DiBerardinis, Janet S. Baum, Melvin W. First, Gari T. Gatwood, Anand K. Se
Edition 4th
Language English
Format PDF
Category Laboratory Books

 

Topics of this Edition:

 

PREFACE xvii

ACKNOWLEDGMENTS xix

ABOUT THE AUTHORS xxi

ABBREVIATIONS xxiii

UNITS xxv

ORGANIZATIONS REFERENCED xxvii

INTRODUCTION xxix

How to Use This Book, xxx

Book Organization, xxxi

Computational Fluid Dynamics, xxxiii

PART IA COMMON ELEMENTS OF LABORATORY DESIGN 1

1 Building Considerations 3

1.1 Guiding Concepts, 3

1.2 Building Layout, 3

1.3 Guiding Principles for Building Heating, Ventilating, and Air-Conditioning Systems, 44

1.4 Guiding Concepts for Laboratory Building Loss Prevention, Industrial Hygiene, and Personal Safety, 51

1.5 Miscellaneous Services, 56

2 Laboratory Considerations 65

PART IB COMMON ELEMENTS OF RENOVATIONS 109

3 Renovations: Building Considerations 123

3.1 Guiding Concepts, 123

3.2 Building Layout, 125

3.3 Heating, Ventilating, and Air-Conditioning Systems, 129

3.4 Loss Prevention, Industrial Hygiene, and Personal Safety, 133

3.5 Miscellaneous Services, 134

4 Renovations: Laboratory Considerations 136

4.1 Guiding Concepts, 136

4.2 Laboratory Layout, 137

4.3 Heating, Ventilating, and Air-Conditioning Systems, 138

4.4 Loss Prevention, Industrial Hygiene, and Personal Safety, 138

PART II DESIGN GUIDELINES FOR A NUMBER OF COMMONLY USED LABORATORIES 141

5 General or Analytical Chemistry Laboratory 143

5.1 Description, 143

5.2 Laboratory Layout, 144

5.3 Heating, Ventilating, and Air-Conditioning, 146

5.4 Loss Prevention, Industrial Hygiene, and Personal Safety, 149

5.5 Special Requirements, 149

6 High-Toxicity Laboratory 150

6.1 Description, 150

6.2 Laboratory Layout, 151

6.3 Heating, Ventilating, and Air-Conditioning, 153

6.4 Loss Prevention, Industrial Hygiene, and Personal Safety, 154

6.5 Special Requirements, 155

7 Nanotechnology Laboratories 156

7.1 Description, 156

7.2 Laboratory Layout, 156

7.3 Heating, Ventilating, and Air-Conditioning, 157

7.4 Loss Prevention, Industrial Hygiene, and Personal Safety, 158

8 Engineering Laboratories 160

8.1 Description, 160

8.2 Engineering Disciplines and Some of Their Most Common Laboratory Types, 160

8.3 Wind Tunnel Laboratory, 161

8.4 Jet and Rocket Propulsion Laboratory, 162

8.5 Hydraulics Laboratory, 164

8.6 Material Analysis and Testing Laboratory, 165

8.7 Electrical Circuits, Motors, and Generators Laboratory, 165

8.8 Foundry Laboratory, 167

8.9 Internal Combustion and Gas Turbine Engine Laboratory, 169

9 Pilot Plant: Chemical, Engineering, and Biological 173

9.1 Description, 173

9.2 Pilot Plant Layout, 174

9.3 Heating, Ventilating, and Air-Conditioning, 174

9.4 Loss Prevention, Industrial Hygiene, and Personal Safety, 175

9.5 Special Requirements, 175

10 Physics Laboratory 177

10.1 Description, 177

10.2 Laboratory Layout, 178

10.3 Heating, Ventilating, and Air-Conditioning, 179

10.4 Loss Prevention, Industrial Hygiene, and Personal Safety, 179

10.5 Special Requirements, 181

11 Controlled Environment Room: Hot or Cold 182

11.1 Description, 182

11.2 Laboratory Layout, 183

11.3 Heating, Ventilating, and Air-Conditioning, 183

11.4 Loss Prevention, 185

11.5 Special Requirements, 185

12 High-Pressure Laboratory 187

12.1 Description, 187

12.2 Laboratory Layout, 188

12.3 Heating, Ventilating, and Air-Conditioning, 188

12.4 Loss Prevention, Industrial Hygiene, and Personal Safety, 189

12.5 Special Requirements, 189

13 Radiation Laboratory 190

13.1 Description, 190

13.2 Laboratory Layout, 191

13.3 Heating, Ventilating, and Air-Conditioning, 194

13.4 Loss Prevention, Industrial Hygiene, and Personal Safety, 195

13.5 Special Considerations, 195

14 Biosafety Laboratory 196

14.1 Description, 196

14.2 Laboratory Layout, 202

14.3 Heating, Ventilating, and Air-Conditioning, 212

14.4 Loss Prevention, Industrial Hygiene, and Personal Safety, 213

14.5 Special Requirements, 213

15 Clinical Laboratories 216

15.1 Description, 216

15.2 Laboratory Layout, 218

15.3 Heating, Ventilating, and Air-Conditioning, 222

15.4 Loss Prevention, Industrial Hygiene, and Personal Safety, 223

16 Teaching Laboratory 227

16.1 Description, 227

16.2 Laboratory Layout, 228

16.3 Heating, Ventilating, and Air-Conditioning, 234

16.4 Loss Prevention, Industrial Hygiene, and Personal Safety, 235

17 Gross Anatomy Laboratory 238

17.1 Description, 238

17.2 Laboratory Layout, 239

17.3 Heating, Ventilating, and Air-Conditioning, 243

17.4 Loss Prevention, Industrial Hygiene, and Personal Safety, 244

17.5 Security, 245

18 Pathology Laboratory 246

18.1 Description, 246

18.2 Laboratory Layout, 249

18.3 Heating, Ventilating, and Air-Conditioning, 251

18.4 Loss Prevention, Industrial Hygiene, and Personal Safety, 251

18.5 Special Requirements, 252

19 Autopsy Laboratory 253

19.1 Description, 253

19.2 Laboratory Layout, 255

19.3 Heating, Ventilating, and Air-Conditioning, 260

19.4 Loss Prevention, Industrial Hygiene, and Personal Safety, 261

20 Morgue Facility 262

20.1 Description, 262

20.2 Laboratory Layout, 265

20.3 Heating, Ventilating, and Air-Conditioning, 269

20.4 Loss Prevention, Industrial Hygiene, and Personal Safety, 269

21 Open or Team Research Laboratory 271

21.1 Description, 271

21.2 Laboratory Layout, 272

21.3 Heating, Ventilating, and Air-Conditioning, 275

21.4 Loss Prevention, Industrial Hygiene, and Personal Safety, 275

21.5 Special Considerations, 276

22 Animal Research Laboratory 277

22.1 Description, 277

22.2 Laboratory Layout, 279

22.3 Heating, Ventilating, and Air-Conditioning, 292

22.4 Loss Prevention, Industrial Hygiene, and Personal Safety, 296

22.5 Special Requirements, 297

23 Microelectronics and Cleanroom Laboratories 299

23.1 Description, 299

23.2 Laboratory Layout, 303

23.3 Heating, Ventilating, and Air Conditioning, 307

23.4 Loss Prevention, Industrial Hygiene, and Personnel Safety, 310

23.5 Special Requirements, 312

23.6 Renovations, 314

24 Printmaking Studio 315

24.1 Description, 315

24.2 Print Studio Layout, 317

24.3 Heating, Ventilating, and Air-Conditioning, 318

24.4 Loss Prevention, Industrial Hygiene, and Personal Safety, 321

PART III LABORATORY SUPPORT SERVICES 325

25 Imaging and Photographic Facilities 327

25.1 Introduction, 327

25.2 Photographic And Imaging Facility Layouts, 331

25.3 Heating, Ventilating, and Air-Conditioning, 334

25.4 Loss Prevention, Industrial Hygiene, and Personal Safety, 336

25.5 Special Requirements, 337

26 Support Shops 339

26.1 Description, 339

26.2 Layout, 340

26.3 Heating, Ventilating, and Air-Conditioning, 344

26.4 Loss Prevention, Industrial Hygiene, and Personal Safety, 346

26.5 Special Requirements, 346

27 Hazardous Chemical, Radioactive, and Biological Waste-Handling Rooms 348

27.1 Guiding Concepts, 348

27.2 Layout, 351

27.3 Heating, Ventilating, and Air-Conditioning, 356

27.4 Loss Prevention, Industrial Hygiene, and Personal Safety, 358

27.5 Special Requirements, 358

28 Laboratory Storerooms 360

28.1 Description, 360

28.2 Layout, 363

28.3 Heating, Ventilating, and Air-Conditioning, 366

28.4 Loss Prevention, Industrial Hygiene, and Personal Safety, 367

28.5 Special Requirements, 368

PART IV HVAC SYSTEMS 369

29 HVAC Systems 371

29.1 Description, 371

29.2 Air-Conditioning Systems, 371

29.3 HVAC System Design and Description, 376

29.4 System Descriptions and Strategies, 377

29.5 Humidification and Dehumidification, 386

29.6 Space Pressure Control, 389

29.7 Automatic Control System, 391

30 Fans 392

30.1 Fan Terminology, 392

30.2 Exhaust Fan Specifications, 393

30.3 Atmospheric Dispersion, 394

30.4 Fan Laws, 394

30.5 Fan Selection, 395

30.6 Fan Performance, 396

31 Air Cleaning 397

31.1 Introduction, 397

31.2 Air-Cleaning Equipment for Laboratories, 398

32 Laboratory Hoods and Other Exhaust Air Contaminant-Capture Facilities and Equipment 404

32.1 Introduction, 404

32.2 Conventional Bypass Chemical Fume Hoods, 405

32.3 Auxiliary Air Chemical Fume Hoods, 409

32.4 Perchloric Acid Fume Hoods, 411

32.5 Hoods for Work With Radioactive Materials, 411

32.6 Variable Air-Volume Hoods, 411

32.7 High-Performance Hoods, 412

32.8 Gloveboxes, 412

32.9 Biological Safety Cabinets, 413

32.10 Capture (Exterior) Hoods, 416

32.11 Ductless Hoods, 416

32.12 Performance Tests, 420

33 Exhaust Air Ducts and Accessories 422

33.1 Introduction, 422

33.2 Exhust Duct Considerations, 423

33.3 Exhust System Classification, 424

33.4 Duct Accessories, 424

34 Variable-Air-Volume Systems 426

34.1 Introduction, 426

34.2 VAV Hoods, 427

34.3 Good Design Practices for Vav Systems, 428

34.4 Variable-Volume Exhaust System Operational Concept, 428

34.5 VAV System Controls and Components, 429

34.6 VAV System Fan Controls and Components, 431

34.7 VAV System Duct Configurations, 434

35 Energy Conservation 436

35.1 Introduction, 436

35.2 Recent Trends, 437

35.3 Exhaust Ventilation for Contamination Control, 440

35.4 Lighting, 448

35.5 Thermal Insulation, 448

35.6 Humidity Control, 448

35.7 Evaporative Cooling, 449

35.8 Water Conservation, 449

35.9 Efficient Operating Strategies, 449

PART V ADMINISTRATIVE PROCEDURES 451

36 Project Execution and Bidding Procedures 453

36.1 Guiding Concepts, 453

36.2 Implementation, 454

36.3 Bid Form, 456

36.4 Contract, 457

36.5 Change Orders, 457

36.6 Construction Inspections, 458

36.7 Punch List, 458

36.8 Additional Testing and Acceptance, 458

36.9 Beneficial Occupancy, 459

 

Clinical Laboratory Management

 

 

36.10 Final Acceptance and Commissioning, 459

37 Commissioning and Final Acceptance Criteria 460

37.1 Guiding Concepts, 460

37.2 Design, Construction, and Preoccupancy Checklists, 460

37.3 Heating, Ventilating, and Air-Conditioning, 462

37.4 Loss Prevention, Industrial Hygiene, and Personal Safety, 466

37.5 Project Commissioning, 467

38 Sustainable Laboratory Design 471

38.1 Introduction, 471

38.2 Laboratory Construction Materials, 472

38.3 Heating, Ventilating, and Air-Conditioning, 474

38.4 Loss Prevention, Industrial Hygiene, and Personal Safety, 477

38.5 Miscellaneous Services, 477

38.6 Lighting, 478

38.7 Submetering, 479

38.8 Additional Background Material, 479

PART VI APPENDIXES 481

Appendix A Emergency Showers 483

Appendix B Emergency Eyewash Units 485

Appendix C Signs 486

Appendix D Stack Design 489

Appendix E Matrix of Building Consideration for Specific

Laboratory Types 495

REFERENCES 500

INDEX 509

 

 

 

Introduction:

Today, the laboratory is an incubator for the discoveries of tomorrow. The nature of laboratory work requires the use of potentially hazardous materials, complex equipment that must be combined with internal procedures and technical procedures. Therefore, it is important that the laboratory establishes safety and health first. The design, construction and operation of labs and labs alone can be cumbersome and difficult, requiring a balance of size, cost, and variability when utilizing work capacity.

 

Adjacency bubble diagram IMAGE

Safe and efficient As new technologies emerge and new discoveries are made, laboratories must evolve to stay ahead of research. An important part of this change is the implementation of risk assessments that address a wide range of laboratory conditions. Risk assessments should be conducted to determine the risk and the construction or safety procedures that should be used to ensure the safety of workers and the environment. Risk assessment is a specialized and redefining process that addresses the appropriate objectives for agent risk and laboratory work. The results of the risk assessment should be documented and kept on file at the facility on a permanent basis.

The problems identified in the risk assessment should be addressed in the corrective action plan which should be used to follow the corrective action. Regular risk assessments should be carried out until remedied.

Commissioning is a great process for validating and documenting that a facility and its structures are planned, designed, installed, tested, and able to being operated and maintained to carry out in conformity with the layout rationale. Commissioning starts with the making plans segment of a given venture and proceeds thru layout, construction, start-up, training, acceptance, and early occupancy. The commissioning manner is designed to make certain compliance with the layout rationale of the facility.

Commissioning partly makes a specialty of how the engineering controls observe the general constructing operations. There are several different tactics that can be taken into consideration as a part of the layout and persevering with the operation of a secure laboratory. These consist of improvement of widespread working procedures, verification of character and included structures, certification of specialized laboratories, and compliance to country-wide and global requirements or relevant neighborhood policies.

This -e-book gives a clean to apply roadmap for proprietors and architects to fulfill the numerous demanding situations inherent in laboratories from the most effective to the maximum complex. It brings collectively the various specialists who’re vital to a successful layout: architects, engineers, fitness and protection specialists, and give up users. It gives the layout group vital data for them to invite the best questions and decide what’s the pleasant layout for the unique forms of laboratories desired, at the same time as guiding them withinside the compliance with the applicable policies and contemporary pleasant practices.

 

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