Guyton and Hall Textbook of Medical Physiology 12th edition pdf

Guyton and Hall PDF Free (12th Ed) Textbook of Medical Physiology

In this blog post, Guyton and Hall Textbook of Medical Physiology 12th edition PDF Free with google drive link. John E. Hall, Michael E. Hal has written a series of books which you can also download on this website. This textbook is an excellent resource for mastering essential knowledge of human physiology. Learn and remember vital concepts easily thanks to short, easy-to-read, masterfully edited chapters and an easy-to-use, full-colour layout. See the basics applied to real-life situations with clinical vignettes throughout the text. Discover the newest in physiology with updates reflecting the latest advances in molecular biology, cardiovascular, neurophysiology, and gastrointestinal topics.


Book Name Guyton and Hall Medical Physiology
Author of Book John E. Hall, Michael E. Hal
Edition 12th
Language English
Format PDF
Category Guyton and Hall Books (click)



Now we check the preface of Guyton and hall textbook of medical physiology 12th ed, the first edition of the Medical Physiology Textbook was written by Arthur C. Guyton almost 50 years ago. Unlike many major medical textbooks, which often have 20 or more authors, the first eight editions of the Medical Physiology Textbook were written entirely by Dr Guyton with each new edition arriving on schedule for almost 40 years. Over the years, Dr. Guyton’s textbook was widely used around the world and translated into 13 languages. One of the main reasons for the book’s unprecedented success was its amazing ability to explain complex physiological principles in language easily understood by students. His main goal with each issue was to instruct students in physiology, not to impress his professional colleagues. Textbook of Guyton and Hall Medical Physiology 11th Edition PDF free written by  John E. Hall.

Arthur C. Guyton’s writing style always kept the tone of a teacher talking to his students. I had the privilege of working closely with Dr. Guyton for almost 30 years and the honour of helping him with the ninth and tenth editions. For the eleventh edition, I have the same goal as in previous editions: to explain, in language easily understood by students, how the different cells, tissues, and organs of the human body work together to sustain life. This task has been challenging and exciting because our growing knowledge of physiology continues to unravel new mysteries of bodily functions. Many new techniques have been developed for learning about molecular and cellular physiology. We can increasingly present the principles of physiology in the terminology of the physical and molecular sciences rather than simply in a series of separate and inexplicable biological phenomena. This change is welcome, but it also makes reviewing each chapter a must, grasp a need. In this edition, I have tried to maintain the same unified organization of the text that has been helpful to students in the past and to ensure that the book is comprehensive enough that students wish to use it in later life as a basis for their professional studies careers. I hope this textbook conveys the majesty of the human body and its many functions and encourages students to study physiology throughout their careers.

Physiology is the link between basic science and medicine. The great beauty of physiology is that it integrates the individual functions of all the different cells, tissues, and organs of the body into one functional whole, the human body. In fact, the human body is much more than the sum of its parts, and life is based on this total function, not just the function of individual parts of the body isolated from each other. This brings us to an important question: How do the separate organs and systems coordinate to keep the entire body functioning properly? Fortunately, our bodies are endowed with a vast network of feedback controls that strike the necessary balances without which we could not live. Physiologists call this high level of internal body control homeostasis. In disease states, functional balances are often seriously disturbed and homeostasis is impaired. And, when even a single disturbance reaches a limit, the whole body can no longer live. One of the objectives of this text, therefore, is to emphasize the effectiveness and beauty of the body’s homeostasis mechanisms, as well as to present their abnormal function in disease.


Guyton Hall 14th edition
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Topics of this Edition:

Guyton and Hall PDF Free (12th Ed) Textbook of Medical Physiology contains the following chapters in this version.

Unit I: Introduction to Physiology: The Cell and General Physiology
Unit II: Membrane Physiology, Nerve, and Muscle
Unit III: The Heart
Unit IV: The Circulation
Unit V: The Body Fluids and Kidneys
Unit VI: Blood Cells, Immunity, and Blood Coagulation
Unit VII: Respiration
Unit VIII: Aviation, Space, and Deep-Sea Diving Physiology
Unit IX: The Nervous System: A. General Principles and Sensory Physiology
Unit X: The Nervous System: B. The Special Senses
Unit XI: The Nervous System: C. Motor and Integrative Neurophysiology
Unit XII: Gastrointestinal Physiology
Unit XIII: Metabolism and Temperature Regulation
Unit XIV: Endocrinology and Reproduction
Unit XV: Sports Physiology

Demo Content:

You can read example content of Guyton & Hall 12th edition Medical Physiology pdf free


Respiration provides oxygen to the tissues and removes carbon dioxide. The four major functions of respiration are (1) pulmonary ventilation, which means the inflow and outflow of air between the atmosphere and the lung alveoli; (2) diffusion of oxygen and carbon dioxide between the alveoli and the blood; (3) transport of oxygen and carbon dioxide in the blood and body fluids to and from the body’s tissue cells; and (4) regulation of ventilation and other facets of respiration. This chapter is a discussion of pulmonary ventilation, and the subsequent five chapters cover other respiratory functions plus the physiology of special respiratory abnormalities.

Respiration system

Muscles That Cause Lung Expansion and Contraction

The lungs can be expanded and contracted in two ways: (1) by downward and upward movement of the diaphragm to lengthen or shorten the chest cavity, and (2) by elevation and depression of the ribs to increase and decrease the anteroposterior diameter of the chest cavity. Figure 37-1 shows these two methods. Normal quiet breathing is accomplished almost entirely by the first method, that is, by the movement of the diaphragm. During inspiration, contraction of the diaphragm pulls the lower surfaces of the lungs downward. Then, during expiration, the diaphragm simply relaxes, and the elastic recoil of the lungs, chest wall and abdominal structures compresses the lungs and expels the air. During heavy breathing, however, the elastic forces are not powerful enough to cause the necessary rapid expiration, so the extra force is achieved mainly by contraction of the abdominal muscles, which pushes the abdominal contents upward against the bottom of the diaphragm, thereby compressing the lungs.


Another boo is here Ganong’s Review of Medical Physiology 26th edition 


The second method for expanding the lungs is to raise the rib cage. This expands the lungs because, in the natural resting position, the ribs slant downward, as shown on the left side of Figure 37-1, thus allowing the sternum to fall backwards toward the vertebral column. When the rib cage is elevated, however, the ribs project almost directly forward, so the sternum also moves forward, away from the spine, making the anteroposterior thickness of the chest about 20 % greater during maximum inspiration than during expiration. Therefore, all the muscles that elevate the chest cage are classified as muscles of inspiration, and those muscles that depress the chest cage are classified as muscles of expiration. The most important muscles that raise the rib cage are the external intercostals, but others that help are the (1) sternocleidomastoid muscles, which lift upward on the sternum; (2) anterior serrate, which lift many of the ribs; and (3) scalene, which lift the first two ribs.

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