In this medical blog post we are sharing Physics of Thermal Therapy: Fundamentals and Clinical Applications Pdf, The field of thermal therapy has been growing tenaciously in recent decades. The application of heat to living tissue, from mild hyperthermia to high-temperature thermal ablation, has produced a host of well-documented genetic, cellular, and physiological responses that are being intensively investigated for medical applications, particularly for the treatment of solid cancerous tumors using image guidance. The controlled application of thermal energy to living tissue has proven to be a major challenge, requiring the expertise of multiple disciplines, which has led to the development of many sophisticated preclinical and clinical treatment devices and techniques. Physics of Thermal Therapy: Fundamentals and Clinical Applications captures the breadth and depth of this highly multidisciplinary field.
What is thermal Therapy?
Heat therapy, also called thermotherapy, is the use of heat in therapy, such as for pain relief and health. It can take the form of a hot cloth, a hot water bottle, an ultrasound, a heating pad, hydrocollator packs, whirlpools, cordless FIR heat therapy wraps, and others.
|PDF Book||Physics of Thermal Therapy: Fundamentals and Clinical Applications|
Focusing on applications in cancer treatment, this book covers the basic principles, practicalities, and clinical applications of thermal therapy. An overview of the fundamentals shows how the use of controlled heat in medicine and biology involves electromagnetism, acoustics, thermodynamics, heat transfer, and imaging sciences. The book reviews the challenges in the use of thermal energy in living tissues and explores genetic, cellular, and physiological responses that can be employed in the fight against cancer from physics and engineering perspectives. It also highlights recent advances, including the treatment of solid tumors using image-guided thermal therapy, microbubbles, nanoparticles, and other cutting-edge techniques.
Topics of Physics of Thermal Therapy
Chapter 1 – Fundamentals of Bioheat Transfer
Chapter 2 – Thermal Dose Models: Irreversible Alterations in Tissues
Chapter 3 – Practical Clinical Thermometry
Chapter 4 – Physics of Electromagnetic Energy Sources
Chapter 5 – The Physics of Ultrasound Energy Sources
Chapter 6 – Numerical Modeling for Simulation and Treatment Planning of Thermal Therapy: Ultrasound
Chapter 7 – Numerical Modeling for Simulation and Treatment Planning of Thermal Therapy
Chapter 8 – External Electromagnetic Methods and Devices
Chapter 9 – Interstitial Electromagnetic Devices for Thermal Ablation
Chapter 10 – Clinical External Ultrasonic Treatment Devices
Chapter 11 – Endocavity and Catheter-Based Ultrasound Devices
Chapter 12 – Evolving Tools for Navigated Image-Guided Thermal Cancer Therapy
Chapter 13 – Temperature Imaging Using Ultrasound
Chapter 14 – Focused Ultrasound Applications for Brain Cancer
Chapter 15 – Extracorporeal Ultrasound-Guided High-Intensity Focused Ultrasound Ablation for Cancer Patients
Chapter 16 – Using Hyperthermia to Augment Drug Delivery
Chapter 17 – Magnetic Nanoparticles for Cancer Therapy
Chapter 18 – Application of Gold Nanoparticles (GNP) in Laser Thermal Therapy
Chapter 19 – Thermochemical Ablation
The science of heat transfer deals with the movement of thermal energy through a defined space under the action of a temperature gradient. Consequently, a fundamental consideration in understanding a heat transfer process is that it must obey the law of conservation of energy, or the first law of thermodynamics. Likewise, the process must also obey the second law of thermodynamics, which, for most practical applications, means that heat will flow only from a region of higher temperature to one of lower temperature. We make direct and repeated use of thermodynamics in the study of heat transfer phenomena, although thermodynamics does not incorporate the tools to tell us the details of how heat flows down a spatial temperature gradient.
A more complete analysis of heat transfer depends on more information about the mechanisms by which energy is driven from a higher temperature to a lower temperature. Long experience has shown us that there are three main mechanisms of action: conduction, convection and radiation. The study of heat transfer involves developing a quantitative representation of each of the mechanisms that can be applied in the context of conservation of energy to arrive at a general description of how the movement of heat by all relevant mechanisms influences changes in the thermal state of a system. Biological systems have special features beyond inanimate systems that must be incorporated into expressions of heat transfer mechanisms.
Many of these features result in effects that cause mathematical nonlinearities and make the analytical description of bioheat transfer more complex than more routine problems. For that reason, you will find applied numerical methods for the solution of many bioheat transfer problems, including many in this book. The purpose of this chapter is to provide a simple introduction to bioheat transfer principles without attempting to delve into the details of the myriad of specific applications that exist. Subsequent chapters will provide this particular analysis where appropriate.
Heat Transfer Principles
In this section, we will review the general principles of heat transfer analysis without reference to the special features of biological tissues that influence heat transfer and energy balance. These matters will be dealt with in the next section. Here we will first consider the energy balance as it applies to all types of heat transfer processes and then each of the three heat transport mechanisms.
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