Red Book

Red Book 2021-2024 PDF free 32nd Edition

Red Book 2021 Report of the Committee on Infectious Diseases 32edition PDF Free .”See the Red Book.” That has been the watchword of generations of health professionals seeking reliable guidance on the prevention, management, and control of pediatric infectious diseases. 200 childhood infectious diseases.

The 32nd edition provides an evidence-based guide to pediatric infections and vaccines based on the committee’s recommendations, as well as the combined experience of the CDC, FDA, and hundreds of collaborating physicians.



Book Name Red Book 2021
Author of Book David W. Kimberlin MD FAAP (Editor) & Others
Edition 32nd 
Language English
Format PDF
Category Medical Books



The Red Book 2021 pdf free, now in its 32nd edition, has been a unique and valuable source of information on infectious diseases and immunizations for pediatricians since 1938. In the 21st century, with the practice of pediatric infectious diseases changing rapidly and the limited time available For the clinician, the Red Book remains an essential resource for quickly obtaining up-to-date, accurate, and easily accessible information on vaccines and vaccine recommendations, emerging infectious diseases, diagnostic modalities, and treatment recommendations. The American Academy of Pediatrics (AAP) Committee on Infectious Diseases, the editors of the Red Book, and the 500 contributors to the Red Book are dedicated to providing the most up-to-date and accurate information available in the concise and practical format for which the Red Book is known.

As with the 2018 edition, the printed version of the Red Book will be provided to all AAP members as part of their member benefit. This commitment reflects the great interest of the Academy in the needs of its members. Additionally, AAP members will also continue to have access to Red Book content in the Red Book online ( AAP policy statements, clinical reports and technical reports, and recommendations endorsed by the AAP are published on Red Book Online as they become available during the 3 years between Red Book editions, and online chapters are published. They modify as necessary to reflect these changes. The Outbreaks section of Red Book Online is a new resource that concisely summarizes current infectious disease outbreaks affecting the pediatric population that has been identified in various US states. Other types of outbreaks may occasionally be covered based on the situation that requires it. 

Another important resource is the Red Book Online visual library, which is continually being updated and expanded to include more infectious disease images, examples of classical and other radiological findings, and recent information on infectious disease epidemiology. The Infectious Diseases Committee relies on the information and advice of many experts, as evidenced by the extensive list of contributors to the Red Book. In particular, we are indebted to the many contributors to other AAP committees, chapters, and councils; the American Academy of Family Physicians; the American College of Obstetricians and Gynecologists; the American Thoracic Society; the Canadian Pediatric Society; the Centers for Disease Control and Prevention; the US Food and Drug Administration; the National Institutes of Health; the Office of the National Vaccine Program; the Pediatric Infectious Diseases Society; the Latin American Society of Pediatric Infectology; World Health Organization; and many other organizations and individuals who have made this edition possible. In addition, whenever possible, suggestions made by individual AAP members have been incorporated to improve the presentation of information on specific topics and on topic selection.


Topics of this Edition:

Summary of Major Changes in the 2021 Red Book
Section 1: Active and Passive Immunization
Section 2: Recommendations for Care of Children in Special Circumstances
Section 3: Summaries of Infectious Diseases
Section 4: Antimicrobial Agents and Related Therapy
Section 5: Antimicrobial Prophylaxis

These are topics which contains by Red Book 

Major Changes in the 2021 Red Book:

All chapters in the last edition of the Red Book were assessed for relevance in the dynamic environment that is the practice of pediatric medicine today. The School Health chapter was noted to have significant overlap with the Children in Out-of-home Child Care chapter, so they were merged in the 2021 edition into a single chapter titled Children in Group Child Care and Schools. In addition, the Vaccine Injury Table appendix was deleted. Two chapters have been added to the 2021 edition: Pseudomonas aeruginosa Infections and a new Systems-based Treatment Table that is designed to aid in initial antibiotic selections by clinical condition, before the specific pathogen is known.

The 2018 Red Book had 9% fewer chapters compared with the 2015 edition, and yet the total book was 60 pages long. As we started work on the 2021 Red Book, we, therefore, identified the 31 chapters that were 10 pages or longer in the 2018 edition and made a targeted effort to trim them so that all relevant information could more easily and quickly be located. Although some of these 31 chapters (eg, the antibiotic or antiparasitic tables) could not be truncated, we overall achieved our goal by decreasing the 2021 Red Book by 41 pages compared with the 2018 edition.

Every chapter in the 2021 Red Book has been modified since the last edition. The listing below outlines the more major changes throughout the 2021 edition.
Throughout the Red Book, the number of websites where additional current and future information can be obtained has been updated. All websites are in bold type for ease of reference, and all have been verified for accuracy and accessibility.


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Reference to evidence-based policy recommendations from the American Academy of Pediatrics (AAP), the Advisory Committee on Immunization Practices (ACIP) of the Centers for Disease Control and Prevention (CDC), and other select professional organizations have been updated throughout the Red Book.

Standardized approaches to disease prevention through immunizations, antimicrobial prophylaxis, and infection-control practices have been updated throughout the Red Book.
Standardized approaches to disease prevention through immunizations, antimicrobial prophylaxis, and infection-control practices have been updated throughout the Red Book.


The American Academy of Pediatrics (AAP) Committee on Infectious Diseases (COID) is responsible for developing and reviewing the AAP guidance for the management and control of infectious diseases in infants, children, and adolescents. Every 3 years, COID issues the Red Book: Infectious Diseases Committee Report, which contains a composite summary of current recommendations that represent AAP policy on various aspects of infectious diseases, including updated vaccine recommendations for newer American foods. and vaccines authorized by the Drug Administration (FDA) for infants, children and adolescents. These recommendations represent a consensus of opinion based on consideration of the best available evidence by COID members, along with liaison representatives from the Centers for Disease Control and Prevention (CDC), FDA, Institutes of National Health, the National Vaccine. Program Office, the Canadian Pediatric Society, the American Thoracic Society, the Pediatric Infectious Diseases Society, the American Academy of Family Physicians, the American College of Obstetricians and Gynecologists, Red Book consultants, and dozens of contributors.

This edition of the Red Book pdf free is based on information available as of February 2021. The Red Book is your own personal infectious disease advisor, on your shelf and ready for you 24 hours a day, 7 days a week. Arguably most valuable in circumstances where definitive data from randomized controlled trials are lacking. It is in those situations that guidance from experts in the field is most critical, and COID has literally hundreds of years of accumulated experience to apply in such recommendations. The preparation of the Red Book is a team effort in the true sense of the term. A few weeks after the publication of each Red Book edition, all Red Book chapters are sent for updates to lead reviewers who are leading national and international experts in their specific areas.


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For the 2021 Red Book, a third of the lead reviewers were new to this process, ensuring that the most up-to-date information has been included in this new edition. After review by the lead reviewer, each chapter is returned to the assigned associate editor to incorporate the reviewer’s edits. The chapter is then distributed to CDC and FDA content experts and members of all AAP Sections, Committees, and Councils who agree to revise specific chapters for their additional editions as needed, after which it is returned. again to the Associate Editor assigned for harmonization and incorporation of modifications as appropriate.

A final review of the chapter is then completed by two designated COID reviewers, and it is returned to the assigned associate editor for any additional necessary edits. Chapters that require full committee consideration are then discussed at the “Marathon Meeting,” where the chapters are finalized. This is followed by proofreading by Senior Medical Editor and Editor Jennifer Shaw, and the book is reviewed by Red Book reviewers appointed by the AAP Board of Directors. In total, 1000 hands have touched the Red Book 2021 before its publication! That so many collaborators dedicate so much time and experience



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