Review of Pharmacology 9th Edition by Gobind Rai Garg and Sparsh Gupta has a series in pharmacology related medical books. This book is also known as CRG. Pharmacology is one of the most difficult and at the same time one of the most important subjects in various postgraduate entrance examinations. As we have experienced, most students who prepare for the postgraduate entrance exams are in a dilemma, whether they are pursuing an earlier education or retiring. Integrated study takes a lot of time and due to heavy textbooks, some important questions are likely to be lost. In a retrospective study, students answer frequently asked MCQs but new questions are not covered. We have tried to overcome the shortcomings of both methods while maintaining the advantages.
In this book (Review of Pharmacology 9th Edition) we have given a concise and enriched text in each chapter followed by MCQs from various postgraduate entrance examinations and other important questions likely to come. The text provides the advantage of antegrade study in a short span of time. After going through the book, it will be easier for the student to solve the questions of most recent examinations, which are given at the end of the book.
Table of Contents
Importance of this book:
After going through the ninth edition of Review of Pharmacology medical book, it will be easier for the student to solve the questions of most recent examinations, which are given at the end of the book. More and more questions about new drugs are being asked in the entrance examinations nowadays. These NEW DRUGS have been covered along with the text and a separate chapter has been added at the end. Salient features of the new drugs along with the reference in the text have been included in this chapter.
Recently, the questions are being asked from SOME EMERGING TOPICS like anti-obesity drugs, anti-smoking drugs, drugs for erectile dysfunction and nitric oxide. All these topics have been discussed in a separate chapter. Large number of questions about first choice drugs is being incorporated in the entrance examinations. To cover these questions, a separate chapter entitled “DRUGS OF CHOICE” has been added. Important ADVERSE EFFECTS caused by drugs have also been included. It is very difficult and at times very confusing to remember large number of drugs and adverse effects.
To make learning easy, several easy to grasp MNEMONICS have been given throughout the text. Despite our best efforts, some mistakes might have crept in, which we request all our readers to kindly bring to our notice. Your suggestions, appreciation and criticism are most welcome. The most important thing is that Harrison’s Principles of Internal Medicine‘s refrences are used in this book.
Description:
Book Name
Review of Pharmacology
Author of Book
Gobind Rai Garg and Sparsh Gupta
Edition
9th
Language
English
Format
PDF
Price
PDF free
Topics of this Edition:
This free pharmacology medical book contains the given below topics in ninth edition of review by Gobind Rai Garg and Sparsh Gupta.
Chapter-01_History of Pharmacology
Chapter-02_General Pharmacology
Chapter-03_Autonomic Nervous System
Chapter-04_Autacoids
Chapter-05_Cardiovascular System
Chapter-06_Kidney
Chapter-07_Endocrinology
Chapter-08_Central Nervous System
Chapter-09_Anaesthesia
Chapter-10_Hematology
Chapter-11_Respiratory System
Chapter-12_Gastrointestinal Tract
Chapter-13_Chemotherapy A General Considerations and Non-specific Antimicrobial Agents
Chapter-14_Chemotherapy B Antimicrobials for Specific Conditions
Chapter-15_Chemotherapy C Antineoplastic Drugs
Chapter-16_Immunomodulators
Chapter-17_Other Topics and Adverse Effects
Chapter-18_Drugs of Choice
Chapter-19_New Drugs
Chapter-20_Recent Topics
Chapter-21_Latest Papers
Image Based Questions
What is History of Pharmacology?
Pharmacology is the science dealing with drugs. It is divided into several branches like pharmacokinetics, pharmacodynamics, pharmacotherapeutics, chemotherapy and toxicology etc.
Oswald Schmiedberg is the father of Pharmacology. Pharmacology emerged as a discipline in the 19th century, derived from research in fields such as organic chemistry and physiology. Oswald Schmidtberg, now born in Latvia in 1838, is considered the father of pharmacology.
When a drug is administered to a person, it will exert some effect on the patient (Pharmacodynamics) and the patient’s body will have some effect on the drug (Pharmacokinetics). These are the two major branches of pharmacology. Before discussing about these branches, we will summarize, how drugs can be administered to a patient (with some important points only).
Routes of Drug Administration
Local Routes:
Local Routes include topical application on the skin and mucous membranes as well as the routes like intra-articular (e.g. hydrocortisone) and intrathecal (e.g. amphotericin B).
Systemic Routes include oral, sublingual, transdermal, nasal, inhalational, rectal and other parenteral routes (intravenous, intramuscular, intradermal and subcutaneous).
Oral route is safer and economical but several drugs are not effective by this route because of high first pass metabolism in the liver and intestinal wall (e.g. nitrates, lignocaine, propanolol, pethidine).
Sublingual route avoids first pass metabolism, can be used in emergencies, can be selfadministered and also after getting the desired action, rest of the drug can be spitted. Drugs like nitroglycerine, isosorbide dinitrate, clonidine, nifedipine etc. can be administered by sublingual route.
Transdermal route is used only for the drugs which are highly lipid soluble and can be absorbed through intact skin. By this route, there is a constant release of the drug (rate of drug delivery to skin is less than the maximum absorptive capacity of the skin so that absorption does not become the limiting factor and there is a constant level of the drug in the blood) and it may be administered less frequently. Nitroglycerine, nicotine, fentanyl and hyoscine are adminstered through transdermat patch. • Drugs administered by nasal route are nafarelin (GnRH agonist), calcitionin and desmopressin.
Inhalational route is the route by which the rate of drug delivery can be controlled like i.v. infusion. The drugs administered by this route include drugs for asthma (e.g., salbutamol, ipratropium, montelukast and inhalational steroids) and inhalational anaesthetic agents like nitrous oxide.
Rectal route avoids first pass metabolism to 50% extent. Diazepam is given by this route in children for febrile seizures.
Intravenously, drugs can be given as bolus or via infusion. other parenteral routes include i.m. and s.c. routes.
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